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In a truly random selection process, a high probability exists that some employees will be selected several times while others may never be selected.
Why? Because after each selection, the employee’s name is returned to the same pool, and he or she becomes just as likely as anyone else to be selected next time. Each employee shall have an equal chance of being tested each time selections are made.

When you test positive or refuse a test, you are not permitted to perform safety-sensitive duties for any DOT-regulated employer until you have seen a Substance Abuse Professional (SAP) and successfully completed the return-to-duty process, which includes a Federal return-to-duty drug and/or alcohol test. Working in a safety-sensitive position before successfully completing the return-to-duty process is a violation of the regulations.

The laboratory that tests your specimen will send your test results to a Medical Review Officer (MRO) and if your result is positive the MRO will call you regarding your test result.  The MRO will discuss with you any possible medication you are taking which could affect the outcome of the drug test.  If there is a prescription the MRO will ask for the prescription information and pharmacy and verify this.  If everything checks out your test result will have a final result of negative.

No, random testing cannot typically be substituted for required follow-up testing. Random testing and follow-up testing serve different purposes within a drug testing program.
While both types of testing aim to ensure adherence to drug and alcohol policies and promote safety, they serve distinct purposes and cannot be used interchangeably. Random testing helps to deter substance use among all employees, while follow-up testing is targeted toward individuals with a history of substance abuse or positive test results to support their recovery and ensure ongoing compliance.